snoRNAs in S. cerevisiae

This table lists all of the snoRNA genes identified in S. cerevisiae, in the box C/D, box H/ACA, or MRP families.

Most of the snoRNAs are involved in RNA processing, most in either 2'-O-methylation or pseudouridylation of nucleotides within RNA molecules (target sites listed below; view known modifications and sequence context). A few are required for endonucleatic cleavages of the primary 35S rRNA transcript to generate the mature 18S, 25S, and 5.8S rRNA molecules. NA indicates that a given snoRNA is not involved in that process. For a diagram of the rDNA repeat showing the transcribed region and processing sites, see the RDN1 summary paragraph This table also provides information about the genomic organization of each snoRNA, whether it is present as a monocistronic transcript, within a polycistronic transcript containing multiple snoRNAs, or within an intron of a protein coding gene. Most snoRNA genes are transcribed by RNA polymerase II, except snR52 is transcribed by RNA polymerase III.

Many thanks to Wayne Decatur and Dorota Piekna-Przybylska for providing the coordinates of the modification sites within the 18S and 25S rRNAs with respect to the genome of S. cerevisiae. Note that older papers have used alternate coordinate systems; links to tables providing the correspondance between old and the current coordinates are here:

18S ribose methylations | 18S pseudouridylations | 25S ribose methylations | 25S pseudouridylations

For more detailed information about the snoRNAs, see the SGD Locus Summaries for each or the yeast snoRNA database at UMass Amherst.

snoRNAs in S. cerevisiae
compiled June 2007, updated June 2008

Gene Name

Other Names

Family

Process

Target Site(s) of Modification
(2'-O-methylation or pseudouridylation)

Role in rRNA Cleavage during Ribosome Biogenesis

Genomic Organization

NME1 MRP MRP cleavage NA essential RNA involved in cleavage at site A3, between the 5.8S and 25S rRNAs (though note that cleavage at A3 is not essential) ^{(6, 14, 22, 25)} monocistronic ⁽¹⁸⁾

snR3 H/ACA pseudouridylation 25S-psi-2129
25S-psi-2133
25S-psi-2264 ^{(17, 21, 24)} NA monocistronic ⁽¹⁸⁾

snR4 C/D unknown no target site predicted within rRNAs ⁽¹⁸⁾ NA monocistronic ⁽¹⁸⁾

snR5 H/ACA pseudouridylation 25S-psi-1004
25S-psi-1124 ⁽⁸⁾ NA monocistronic ⁽¹⁸⁾

snR8 H/ACA pseudouridylation 25S-psi-960
25S-psi-986 ⁽¹⁷⁾ NA monocistronic ⁽¹⁸⁾

snR9 H/ACA pseudouridylation 25S-psi-2340 ⁽²¹⁾ NA monocistronic ⁽¹⁸⁾

snR10 H/ACA cleavage
pseudouridylation 25S-psi-2923 ⁽¹⁷⁾ non-essential RNA involved in cleavages at sites A1 (in the 5'-ETS) and A2 (in ITS1), flanking the 18S rRNA ^{(23, 25)} monocistronic ⁽¹⁸⁾

snR11 H/ACA pseudouridylation 25S-psi-2416 ⁽²⁴⁾ NA monocistronic ⁽¹⁸⁾

snR13 C/D methylation 25S-Am2280
25S-Am2281 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR17a U3 C/D cleavage NA essential RNA involved in cleavages at sites A0 and A1 (in the 5'-ETS) and A2 (in ITS1), flanking the 18S rRNA ^{(3, 9, 25)} monocistronic, contains an intron ⁽¹⁸⁾

snR17b monocistronic, contains an intron ⁽¹⁸⁾

snR18 U18 C/D ^{(3, 9, 25)} methylation ⁽¹⁸⁾ 25S-Am649
25S-Cm650 ⁽¹⁰⁾ NA intronic (within EFB1) ⁽¹⁸⁾

snR24 U24 C/D methylation 25S-Am1449
25S-Cm1437
25S-Gm1450 ⁽¹⁰⁾ NA intronic (within ASC1) ⁽¹⁹⁾

snR30 H/ACA cleavage NA essential RNA involved in cleavages at sites A1 (in the 5'-ETS) and A2 (in ITS1), flanking the 18S rRNA ^{(1, 16, 25)} monocistronic ⁽¹⁸⁾

snR31 H/ACA pseudouridylation 18S-psi-999 ⁽¹⁷⁾ NA monocistronic ⁽¹⁸⁾

snR32 H/ACA pseudouridylation 25S-psi-2191 ⁽¹⁷⁾ NA monocistronic ⁽¹⁸⁾

snR33 H/ACA pseudouridylation 25S-psi-1042 ⁽¹⁷⁾ NA monocistronic ⁽¹⁸⁾

snR34 H/ACA pseudouridylation 25S-psi-2826
25S-psi-2880 ^{(17, 24)} NA monocistronic ⁽¹⁸⁾

snR35 H/ACA pseudouridylation m¹acp³-18S-psi-1191 ⁽²¹⁾ NA monocistronic ⁽¹⁸⁾

snR36 H/ACA pseudouridylation 18S-psi-1187 ⁽⁸⁾ NA monocistronic ⁽¹⁸⁾

snR37 H/ACA pseudouridylation 25S-psi-2944 ⁽¹⁷⁾ NA monocistronic ⁽¹⁸⁾

snR38 C/D methylation 25S-Gm2815 ⁽¹⁰⁾ NA intronic (within TEF4) ⁽¹⁸⁾

snR39 C/D methylation 25S-Am807 ⁽¹⁰⁾ NA intronic (within RPL7A) ⁽¹⁸⁾

snR39B C/D methylation 25S-Gm805 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR40 C/D methylation 18S-Gm1271
25S-Um898 ^{(10, 13)} NA monocistronic ⁽¹⁸⁾

snR41 C/D methylation 18S-Am541
18S-Gm1126 ^{(10, 13)} NA polycistronic (snR41, snR70, and snR51) ⁽⁵⁾

snR42 H/ACA pseudouridylation 25S-psi-2975 ⁽¹⁷⁾ NA monocistronic ⁽¹⁸⁾

snR43 H/ACA pseudouridylation 5.8S-psi-73 ⁽²⁶⁾,
25S-psi-966 ⁽²⁴⁾ NA monocistronic ⁽¹⁸⁾

snR44 H/ACA pseudouridylation 18S-psi-106
25S-psi-1056 ^{(21, 24)} NA intronic (within RPS22B) ⁽¹⁸⁾

snR45 C/D unknown no target site predicted within rRNAs ⁽¹⁸⁾ NA monocistronic ⁽¹⁸⁾

snR46 H/ACA pseudouridylation 25S-psi-2865 ⁽¹⁷⁾ NA monocistronic ⁽¹⁸⁾

snR47 C/D methylation 18S-Am619
25S-Am2220 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR48 C/D methylation 25S-Gm2791
25S-Gm2793 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR49 H/ACA pseudouridylation 18S-psi-120
18S-psi-211
18S-psi-302
25S-psi-990 ^{(21, 24)} NA monocistronic ⁽¹⁸⁾

snR50 C/D methylation 25S-Gm867 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR51 C/D methylation 18S-Am100
25S-Um2729 ⁽¹³⁾ NA polycistronic (snR41, snR70, and snR51) ⁽⁵⁾

snR52 C/D methylation 18S-Am420
25S-Um2921 ^{(11, 13)} NA monocistronic (transcribed by RNA polymerase III) ⁽¹⁸⁾

snR53 C/D methylation 18S-Am796 ⁽¹³⁾ NA polycistronic (snR53 and snR67) ⁽¹⁸⁾

snR54 C/D methylation 18S-Am974 ⁽¹³⁾ NA intronic (within IMD4) ⁽¹⁸⁾

snR55 C/D methylation 18S-Um1269 ⁽¹³⁾ NA polycistronic (snR57, snR55, and snR61) ⁽¹⁸⁾

snR56 C/D methylation 18S-Gm1428 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR57 C/D methylation 18S-Gm1572 ⁽¹³⁾ NA polycistronic (snR57, snR55, and snR61) ⁽¹⁸⁾

snR58 C/D methylation 25S-Cm663 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR59 C/D methylation 25S-Am807 ⁽¹³⁾ NA intronic (within RPL7B) ⁽¹⁸⁾

snR60 C/D methylation 25S-Am817
25S-Gm908 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR61 C/D methylation 25S-Am1133 ⁽¹³⁾ NA polycistronic (snR57, snR55, and snR61) ⁽¹⁸⁾

snR62 C/D methylation 25S-Um1888 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR63 C/D methylation 25S-Am2256 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR64 C/D methylation 25S-Cm2337 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR65 C/D methylation 25S-Um2347 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR66 C/D methylation 25S-Um2417 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR67 C/D methylation 25S-Gm2619
25S-Um2724 ⁽¹³⁾ NA polycistronic (snR53 and snR67) ⁽¹⁸⁾

snR68 C/D methylation 25S-Am2640 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR69 C/D methylation 25S-Cm2948 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR70 C/D methylation 18S-Cm1639 ⁽¹³⁾ NA polycistronic (snR41, snR70, and snR51) ⁽⁵⁾

snR71 C/D methylation 25S-Am2946 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR72 C/D methylation 25S-Am876 ^{(13, 20)} NA polycistronic (snR78, snR77, snR76, snR75, snR74, snR73, and snR72) ^{(20, 5)}

snR73 C/D methylation 25S-Cm2959 ^{(13, 20)} NA

snR74 C/D methylation 18S-Am28 ^{(13, 20)} NA

snR75 C/D methylation 25S-Gm2288 ^{(13, 20)} NA

snR76 C/D methylation 25S-Cm2197 ^{(13, 20)} NA

snR77 C/D methylation 18S-Um578 ^{(13, 20)} NA

snR78 C/D methylation 25S-Um2421 ^{(13, 20)} NA

snR79 C/D methylation 18S-Cm1007 ⁽¹³⁾ NA monocistronic ⁽¹⁸⁾

snR80 H/ACA pseudouridylation 18S-psi-759
25S-psi-776 ^{(21, 24)} NA monocistronic ⁽¹⁸⁾

snR81 H/ACA pseudouridylation 25S-psi-1052
U2-psi-42 ⁽²¹⁾ NA monocistronic ⁽¹⁸⁾

snR82 H/ACA pseudouridylation 25S-psi-1110
25S-psi-2349
25S-psi-2351 ^{(15, 21, 24)} NA monocistronic ⁽¹⁸⁾

snR83 H/ACA pseudouridylation 18S-psi-1290
18S-psi-1415 ^{(21, 24)} NA monocistronic ⁽¹⁸⁾

snR84 H/ACA pseudouridylation 25S-psi-2266 ^{(21, 24)} NA monocistronic ⁽¹⁸⁾

snR85 H/ACA pseudouridylation 18S-psi-1181 ^{(21, 24)} NA monocistronic ⁽¹⁸⁾

snR86 H/ACA pseudouridylation 25S-psi-2314 ⁽²⁴⁾ NA monocistronic ⁽¹⁸⁾

snR87 C/D methylation 18S-Am436 ⁽⁷⁾ NA monocistronic ⁽¹⁸⁾

snR128 U14 C/D cleavage,
methylation 18S-Cm414 ⁽¹⁰⁾ essential RNA involved in cleavages at sites A1 (in the 5'-ETS) and A2 (in ITS1), flanking the 18S rRNA ^{(12, 25)} polycistronic (snR128 and snR190) ⁽⁴⁾

snR161 H/ACA pseudouridylation 18S-psi-632
18S-psi-766 ^{(21, 24)} NA monocistronic ⁽¹⁸⁾

snR189 H/ACA pseudouridylation 18S-psi-466
25S-psi-2735 ⁽²⁴⁾ NA monocistronic ⁽¹⁸⁾

snR190 C/D possibly methylation predicted to guide 25S-Gm2395 but not shown to be active ^{(10, 18)} NA polycistronic (snR128 and snR190) ⁽⁴⁾

snR191 H/ACA pseudouridylation 25S-psi-2258
25S-psi-2260 ⁽²⁾ NA intronic (within NOG2) ⁽¹⁸⁾

snoRNAs in S. cerevisiae compiled June 2007, updated June 2008
Gene Name	Other Names	Family	Process	Target Site(s) of Modification (2'-O-methylation or pseudouridylation)	Role in rRNA Cleavage during Ribosome Biogenesis	Genomic Organization
NME1	MRP	MRP	cleavage	NA	essential RNA involved in cleavage at site A3, between the 5.8S and 25S rRNAs (though note that cleavage at A3 is not essential) ^{(6, 14, 22, 25)}	monocistronic ⁽¹⁸⁾
snR3		H/ACA	pseudouridylation	25S-psi-2129 25S-psi-2133 25S-psi-2264 ^{(17, 21, 24)}	NA	monocistronic ⁽¹⁸⁾
snR4		C/D	unknown	no target site predicted within rRNAs ⁽¹⁸⁾	NA	monocistronic ⁽¹⁸⁾
snR5		H/ACA	pseudouridylation	25S-psi-1004 25S-psi-1124 ⁽⁸⁾	NA	monocistronic ⁽¹⁸⁾
snR8		H/ACA	pseudouridylation	25S-psi-960 25S-psi-986 ⁽¹⁷⁾	NA	monocistronic ⁽¹⁸⁾
snR9		H/ACA	pseudouridylation	25S-psi-2340 ⁽²¹⁾	NA	monocistronic ⁽¹⁸⁾
snR10		H/ACA	cleavage pseudouridylation	25S-psi-2923 ⁽¹⁷⁾	non-essential RNA involved in cleavages at sites A1 (in the 5'-ETS) and A2 (in ITS1), flanking the 18S rRNA ^{(23, 25)}	monocistronic ⁽¹⁸⁾
snR11		H/ACA	pseudouridylation	25S-psi-2416 ⁽²⁴⁾	NA	monocistronic ⁽¹⁸⁾
snR13		C/D	methylation	25S-Am2280 25S-Am2281 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR17a	U3	C/D	cleavage	NA	essential RNA involved in cleavages at sites A0 and A1 (in the 5'-ETS) and A2 (in ITS1), flanking the 18S rRNA ^{(3, 9, 25)}	monocistronic, contains an intron ⁽¹⁸⁾
snR17b	monocistronic, contains an intron ⁽¹⁸⁾
snR18	U18	C/D ^{(3, 9, 25)}	methylation ⁽¹⁸⁾	25S-Am649 25S-Cm650 ⁽¹⁰⁾	NA	intronic (within EFB1) ⁽¹⁸⁾
snR24	U24	C/D	methylation	25S-Am1449 25S-Cm1437 25S-Gm1450 ⁽¹⁰⁾	NA	intronic (within ASC1) ⁽¹⁹⁾
snR30		H/ACA	cleavage	NA	essential RNA involved in cleavages at sites A1 (in the 5'-ETS) and A2 (in ITS1), flanking the 18S rRNA ^{(1, 16, 25)}	monocistronic ⁽¹⁸⁾
snR31		H/ACA	pseudouridylation	18S-psi-999 ⁽¹⁷⁾	NA	monocistronic ⁽¹⁸⁾
snR32		H/ACA	pseudouridylation	25S-psi-2191 ⁽¹⁷⁾	NA	monocistronic ⁽¹⁸⁾
snR33		H/ACA	pseudouridylation	25S-psi-1042 ⁽¹⁷⁾	NA	monocistronic ⁽¹⁸⁾
snR34		H/ACA	pseudouridylation	25S-psi-2826 25S-psi-2880 ^{(17, 24)}	NA	monocistronic ⁽¹⁸⁾
snR35		H/ACA	pseudouridylation	m¹acp³-18S-psi-1191 ⁽²¹⁾	NA	monocistronic ⁽¹⁸⁾
snR36		H/ACA	pseudouridylation	18S-psi-1187 ⁽⁸⁾	NA	monocistronic ⁽¹⁸⁾
snR37		H/ACA	pseudouridylation	25S-psi-2944 ⁽¹⁷⁾	NA	monocistronic ⁽¹⁸⁾
snR38		C/D	methylation	25S-Gm2815 ⁽¹⁰⁾	NA	intronic (within TEF4) ⁽¹⁸⁾
snR39		C/D	methylation	25S-Am807 ⁽¹⁰⁾	NA	intronic (within RPL7A) ⁽¹⁸⁾
snR39B		C/D	methylation	25S-Gm805 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR40		C/D	methylation	18S-Gm1271 25S-Um898 ^{(10, 13)}	NA	monocistronic ⁽¹⁸⁾
snR41		C/D	methylation	18S-Am541 18S-Gm1126 ^{(10, 13)}	NA	polycistronic (snR41, snR70, and snR51) ⁽⁵⁾
snR42		H/ACA	pseudouridylation	25S-psi-2975 ⁽¹⁷⁾	NA	monocistronic ⁽¹⁸⁾
snR43		H/ACA	pseudouridylation	5.8S-psi-73 ⁽²⁶⁾, 25S-psi-966 ⁽²⁴⁾	NA	monocistronic ⁽¹⁸⁾
snR44		H/ACA	pseudouridylation	18S-psi-106 25S-psi-1056 ^{(21, 24)}	NA	intronic (within RPS22B) ⁽¹⁸⁾
snR45		C/D	unknown	no target site predicted within rRNAs ⁽¹⁸⁾	NA	monocistronic ⁽¹⁸⁾
snR46		H/ACA	pseudouridylation	25S-psi-2865 ⁽¹⁷⁾	NA	monocistronic ⁽¹⁸⁾
snR47		C/D	methylation	18S-Am619 25S-Am2220 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR48		C/D	methylation	25S-Gm2791 25S-Gm2793 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR49		H/ACA	pseudouridylation	18S-psi-120 18S-psi-211 18S-psi-302 25S-psi-990 ^{(21, 24)}	NA	monocistronic ⁽¹⁸⁾
snR50		C/D	methylation	25S-Gm867 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR51		C/D	methylation	18S-Am100 25S-Um2729 ⁽¹³⁾	NA	polycistronic (snR41, snR70, and snR51) ⁽⁵⁾
snR52		C/D	methylation	18S-Am420 25S-Um2921 ^{(11, 13)}	NA	monocistronic (transcribed by RNA polymerase III) ⁽¹⁸⁾
snR53		C/D	methylation	18S-Am796 ⁽¹³⁾	NA	polycistronic (snR53 and snR67) ⁽¹⁸⁾
snR54		C/D	methylation	18S-Am974 ⁽¹³⁾	NA	intronic (within IMD4) ⁽¹⁸⁾
snR55		C/D	methylation	18S-Um1269 ⁽¹³⁾	NA	polycistronic (snR57, snR55, and snR61) ⁽¹⁸⁾
snR56		C/D	methylation	18S-Gm1428 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR57		C/D	methylation	18S-Gm1572 ⁽¹³⁾	NA	polycistronic (snR57, snR55, and snR61) ⁽¹⁸⁾
snR58		C/D	methylation	25S-Cm663 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR59		C/D	methylation	25S-Am807 ⁽¹³⁾	NA	intronic (within RPL7B) ⁽¹⁸⁾
snR60		C/D	methylation	25S-Am817 25S-Gm908 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR61		C/D	methylation	25S-Am1133 ⁽¹³⁾	NA	polycistronic (snR57, snR55, and snR61) ⁽¹⁸⁾
snR62		C/D	methylation	25S-Um1888 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR63		C/D	methylation	25S-Am2256 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR64		C/D	methylation	25S-Cm2337 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR65		C/D	methylation	25S-Um2347 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR66		C/D	methylation	25S-Um2417 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR67		C/D	methylation	25S-Gm2619 25S-Um2724 ⁽¹³⁾	NA	polycistronic (snR53 and snR67) ⁽¹⁸⁾
snR68		C/D	methylation	25S-Am2640 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR69		C/D	methylation	25S-Cm2948 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR70		C/D	methylation	18S-Cm1639 ⁽¹³⁾	NA	polycistronic (snR41, snR70, and snR51) ⁽⁵⁾
snR71		C/D	methylation	25S-Am2946 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR72		C/D	methylation	25S-Am876 ^{(13, 20)}	NA	polycistronic (snR78, snR77, snR76, snR75, snR74, snR73, and snR72) ^{(20, 5)}
snR73		C/D	methylation	25S-Cm2959 ^{(13, 20)}	NA
snR74		C/D	methylation	18S-Am28 ^{(13, 20)}	NA
snR75		C/D	methylation	25S-Gm2288 ^{(13, 20)}	NA
snR76		C/D	methylation	25S-Cm2197 ^{(13, 20)}	NA
snR77		C/D	methylation	18S-Um578 ^{(13, 20)}	NA
snR78		C/D	methylation	25S-Um2421 ^{(13, 20)}	NA
snR79		C/D	methylation	18S-Cm1007 ⁽¹³⁾	NA	monocistronic ⁽¹⁸⁾
snR80		H/ACA	pseudouridylation	18S-psi-759 25S-psi-776 ^{(21, 24)}	NA	monocistronic ⁽¹⁸⁾
snR81		H/ACA	pseudouridylation	25S-psi-1052 U2-psi-42 ⁽²¹⁾	NA	monocistronic ⁽¹⁸⁾
snR82		H/ACA	pseudouridylation	25S-psi-1110 25S-psi-2349 25S-psi-2351 ^{(15, 21, 24)}	NA	monocistronic ⁽¹⁸⁾
snR83		H/ACA	pseudouridylation	18S-psi-1290 18S-psi-1415 ^{(21, 24)}	NA	monocistronic ⁽¹⁸⁾
snR84		H/ACA	pseudouridylation	25S-psi-2266 ^{(21, 24)}	NA	monocistronic ⁽¹⁸⁾
snR85		H/ACA	pseudouridylation	18S-psi-1181 ^{(21, 24)}	NA	monocistronic ⁽¹⁸⁾
snR86		H/ACA	pseudouridylation	25S-psi-2314 ⁽²⁴⁾	NA	monocistronic ⁽¹⁸⁾
snR87		C/D	methylation	18S-Am436 ⁽⁷⁾	NA	monocistronic ⁽¹⁸⁾
snR128	U14	C/D	cleavage, methylation	18S-Cm414 ⁽¹⁰⁾	essential RNA involved in cleavages at sites A1 (in the 5'-ETS) and A2 (in ITS1), flanking the 18S rRNA ^{(12, 25)}	polycistronic (snR128 and snR190) ⁽⁴⁾
snR161		H/ACA	pseudouridylation	18S-psi-632 18S-psi-766 ^{(21, 24)}	NA	monocistronic ⁽¹⁸⁾
snR189		H/ACA	pseudouridylation	18S-psi-466 25S-psi-2735 ⁽²⁴⁾	NA	monocistronic ⁽¹⁸⁾
snR190		C/D	possibly methylation	predicted to guide 25S-Gm2395 but not shown to be active ^{(10, 18)}	NA	polycistronic (snR128 and snR190) ⁽⁴⁾
snR191		H/ACA	pseudouridylation	25S-psi-2258 25S-psi-2260 ⁽²⁾	NA	intronic (within NOG2) ⁽¹⁸⁾

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16. Morrissey JP and Tollervey D (1993) Yeast snR30 is a small nucleolar RNA required for 18S rRNA synthesis. Mol Cell Biol 13(4):2469-77


17. Ni J, et al. (1997) Small nucleolar RNAs direct site-specific synthesis of pseudouridine in ribosomal RNA. Cell 89(4):565-73


18. Piekna-Przybylska D, et al. (2007) New bioinformatic tools for analysis of nucleotide modifications in eukaryotic rRNA. RNA 13(3):305-12


19. Qu LH, et al. (1995) U24, a novel intron-encoded small nucleolar RNA with two 12 nt long, phylogenetically conserved complementarities to 28S rRNA. Nucleic Acids Res 23(14):2669-76


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snoRNAs in S. cerevisiae

snoRNAs in S. cerevisiae

Gene Name

Other Names

Family

Process

Target Site(s) of Modification (2'-O-methylation or pseudouridylation)

Role in rRNA Cleavage during Ribosome Biogenesis

Genomic Organization

Target Site(s) of Modification
(2'-O-methylation or pseudouridylation)