SGD^TM is a scientific database of the molecular biology and genetics of the yeast Saccharomyces cerevisiae, which is commonly known as baker's or budding yeast.

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• Genome Snapshot
• New papers added to SGD this week.
• View Genome-wide Analysis papers in SGD.
• Do a literature search.
• Table of Gene Summary Paragraphs (new ones highlighted yellow).

SGD is now hosting the YeastGFP database of global analysis of protein localization studies in the budding yeast, S. cerevisiae, originally designed and built by the laboratories of Erin O'Shea and Jonathan Weissman at the University of California, San Francisco. Links to individual ORFs are available from the Localization Resources pull-down on the right hand side of SGD Locus Summary pages. Select the 'YeastGFP DB (UCSF) at SGD' option. Thanks to Jonathan Weissman and Nick Ingolia for providing the software and files.

The Yeast GO Slims are sets of high-level GO terms that best represent the major biological processes, molecular functions, and cellular components that are found in S. cerevisiae. GO Slim terms are useful in mapping precise, "granular" gene annotations to more general "high-level" terms. These terms have been selected by SGD curators based on annotation statistics and biological significance. Recently, SGD curators reviewed the Yeast GO Slim terms and made necessary updates to the Process set, including the addition of seven new terms. No changes were made to the Function and Component sets of slim terms.

The Yeast GO Slims are available for analysis via the GO Slim Mapper tool and the Advanced Search tool. Mapping of all the yeast gene products to the Yeast GO Slims is also available as a graphical view on the Genome Snapshot page and via the go_slim_mapping.tab file on the FTP site.

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Images of the GFP fusion proteins described in Huh WK et al (2003) Nature 425:686 are now being hosted by the Yeast Resource Center (YeastRC, Seattle). They can be accessed via the Localization Resources pull-down on the right hand side of SGD Locus Summary pages. Select the 'YeastRC Localization (Seattle)' option and follow the View Data hyperlink on the YeastRC page. Thanks to Trisha Davis, Michael Riffle and the Yeast RC for adding the data and help in setting up these links.

SGD has included two new options in the GO Term Finder, a tool for finding significant GO terms shared among a list of genes.

• Name your analysis/search: allows naming of searches in order to keep track of results when performing multiple GO Term Finder analyses.
• Calculate the False Discovery Rate (FDR): calculates the FDR for each term, indicating the expected proportion of false positives among the set of significant results.

The Saccharomyces Genome Database (SGD^TM) project is supported by a P41 grant, National Resources [HG001315], from the National Human Genome Research Institute at the US National Institutes of Health.   The SGD^TM project is located in the Department of Genetics at the School of Medicine, Stanford University. The trademark on SGD^TM is held by The Board of Trustees, Leland Stanford Junior University.

Database Copyright © 1997-2008 The Board of Trustees, Leland Stanford Junior University. Permission to use the information contained in this database was given by the researchers/institutes who contributed or published the information. Users of the database are solely responsible for compliance with any copyright restrictions, including those applying to the author abstracts. Documents from this server are provided "AS-IS" without any warranty, expressed or implied. How to cite SGD.